Wednesday, July 8, 2009

latest on sperm creation from stem cell

this is amazing news this is a short extract from the http://www.bbc.co.uk


Scientists in Newcastle claim to have created human sperm in the laboratory in what they say is a world first.

The researchers believe the work could eventually help men with fertility problems to father a child.
But other experts say they are not convinced that fully developed sperm have been created.
Writing in the journal Stem Cells and Development, the Newcastle team say it will be at least five years before the technique is perfected.

They began with stem cell lines derived from human embryos donated following IVF treatment.
The stem cells had been removed when the embryo was a few days old and were stored in tanks of liquid nitrogen. .....

INFERTILITY AND IVF

Infertility is when a couple fail to conceive (get pregnant) despite having regular unprotected sex. Although one in seven couples has difficulty conceiving, the number of couples who are actually infertile is relatively low.

About 85% of couples will conceive naturally within one year if they have regular unprotected sex. Of 100 couples trying to conceive naturally:

20 will conceive within one month, 70 will conceive within six months, 85 will conceive within one year, 90 will conceive within eighteen months, and 95 will conceive within two years. Therefore, you will only be diagnosed as infertile if you have not managed to have a baby after two years of trying. If you have never conceived a child, it is known as primary infertility. Secondary infertility is when you have had one or more babies in the past, but you are having difficulty conceiving again.
Some women get pregnant very quickly but, for others, it can take longer. Although there is not a cut off point to say when a couple is infertile, it is best to see your GP if you have not conceived after one year of trying.

If you are a woman over the age of 35, or you are already aware that you may have fertility problems, then you should see your GP sooner. They may be able to check for common causes, and suggest treatments that could help. If fertility problems are diagnosed, there are many different treatments and procedures which may be available to you.
For couples who have been trying to conceive for more than three years, the chance of a pregnancy occurring within the next year is 25%, or less.

Diagnosis

About 85% of couples conceive naturally after one year of unprotected sexual intercourse, so if you have not conceived after one year, you should visit your GP.If you are worried about your fertility, or you are a woman over the age of 35, then you should visit your GP sooner. Fertility testing and investigation can be a lengthy process, and female fertility decreases with age, so it is best to make an appointment early on. Your GP will be able to give you advice about what to do next, and will also carry out an initial assessment to look for factors that may be causing your fertility problems.

It is always best for both partners to visit their GP because fertility problems can be caused by a male or female or, in some cases, both. The process of trying to conceive can be a very emotional one, and it is important that you try and support one another, as stress is just one of the many factors that can affect fertility.

Medical, sexual and social history When you visit your GP, they will carry out a full medical, sexual and social history in order to identify any possible factors which may be causing fertility problems. Your GP may discuss the following with you:

Children - your GP will ask a woman if she has given birth previously and will enquire as to whether there were any complications with the pregnancy. They will also ask about any miscarriages. The man will also be asked about whether or not he has had any children from previous relationships. Length of time trying to conceive - if you are young, and in good general health, it is likely that you will be able to conceive naturally. 95% of couples are able to conceive naturally after two years of having unprotected sex. If you have not been trying for a baby for very long, you may be advised to keep trying for a little longer.
Sex - you may feel uncomfortable, or embarrassed, about discussing your sex life with your GP. However, it is very important to be honest and open about this because the problem can sometimes be difficulty with sex which can be easily overcome. Length of time since stopping contraception - your GP will consider the type of contraception you were previously using to see whether it may be affecting your ability to conceive.

Sometimes, it can take a while for certain types of contraception to stop working. Medication - the side effects of some medication can affect fertility. Your GP will therefore look at any medication you are taking and might discuss alternative treatments with you. You should inform your GP about any non-prescription medication that you are taking, including any herbal medicines. Lifestyle - smoking, weight, alcohol consumption and stress can all affect fertility, so your GP may discuss ways that you could improve your lifestyle, and therefore increase your chance of conceiving. After taking a medical, sexual and social history, your GP may conduct a physical examination, or refer you for further tests.

Women --> When carrying out a physical examination, your GP may:
weigh you to see you if you have a healthy body mass index (BMI) for your height and build, examine your pelvic area to check for vaginal infection, or tenderness, which could be an indication of endometriosis, or pelvic inflammatory disease (PID) - see causes section. After your GP has considered your medical history, and carried out a physical examination, they may refer you for further tests and procedures, as outlined below.

Pelvic ultrasound - uses high frequency sound waves to create an image of an organ in your body, in this case an image of your womb and ovaries. Progesterone test - this blood test checks to see if you are ovulating. The test should be taken seven days before you expect a period. Chlamydia test - chlamydia can affect fertility. If you have chlamydia, your GP will be able to prescribe antibiotics to treat it. Thyroid function test - it is estimated that between 1.3-5.1% of infertile women have an abnormal thyroid. Hysterosalpingogram - this is a type of X-ray that checks your fallopian tubes. Laparoscopy - a small cut is made in your lower abdomen and a thin, tubular microscope, called a laparoscope, is used to look more closely at your womb, fallopian tubes and ovaries. Sometimes, dye is injected into the fallopian tubes through the cervix (entrance to the womb) to highlight any blockages.

Men --> During a physical examination your GP may:
check your testicles for any lumps or deformities, and check your penis to look at its shape and structure and to look for any abnormalities. Further testing can include:
Semen analysis - your semen will be tested to see if you have a low sperm count, low sperm mobility, or abnormal sperm. Chlamydia test - chlamydia can affect fertility. If you have chlamydia then your GP will prescribe antibiotics to treat it.

Also check out this website :

http://www.nhs.uk/Conditions/Infertility/Pages/Introduction.aspx

http://www.zitawest.com/

http://www.babycentre.co.uk/preconception

http://en.wikipedia.org/wiki/In_vitro_fertilisation

http://www.nhs.uk/conditions/IVF/Pages/Introduction.aspx

http://news.bbc.co.uk/1/hi/health/1933901.stm